Why it matters: Jaundice can sometimes appear before pain develops. If you notice yellowing, see a doctor immediately.
2. Unexplained Weight Loss
Losing weight without trying—especially 5-10% of your body weight over 6-12 months—is always worth investigating.
What to notice: You’re eating normally, but the pounds are dropping off. This can happen because the pancreas isn’t producing enough digestive enzymes, so food isn’t properly absorbed.
3. Abdominal or Back Pain
Pain from pancreatic cancer often has distinct characteristics.
What to notice:
Location: Upper abdomen, possibly radiating to the back
Timing: May worsen after eating or when lying down
Quality: Dull, aching, or gnawing—not sharp or stabbing
Relief: Often improves when leaning forward
What to do: Persistent pain that doesn’t go away with rest or over-the-counter remedies deserves evaluation.
4. New-Onset Diabetes (Especially After 50)
