The Mayo Clinic reports that hundreds of prescription and over-the-counter drugs can decrease saliva production, including:
Antidepressants and anti-anxiety medications
Blood pressure medications
Antihistamines and decongestants
Pain relievers and muscle relaxants
Important: If dry mouth began after starting a new medication, it is worth discussing alternatives or dosage adjustments with your healthcare provider rather than stopping the drug on your own.3. Dehydration
Sometimes the cause is simple: your body is not getting enough fluids.
While you sleep, your body continues to lose water through breathing, sweating, and normal metabolism. Going to bed even mildly dehydrated can leave you waking up with a noticeably dry mouth and throat.
The solution is not drinking large amounts of water right before bed—which may interrupt sleep—but maintaining steady hydration throughout the day.
4. Aging
As people age, saliva production naturally declines. Adults over 60 are especially prone to dry mouth due to the combined effects of aging, medications, and chronic medical conditions.
Because saliva protects against cavities, infections, and oral discomfort, consistent oral hygiene and routine dental visits become increasingly important with age.
5. Underlying Medical Conditions
